Expression of HIF-1α and VEGF in feline mammary gland carcinomas: association with pathological characteristics and clinical outcomes.
Bo ChenSusanne Je-Han LinWen-Ta LiHui-Wen ChangVictor Fei PangPei-Yi ChuChin-Cheng LeeHiroyuki NakayamaChing-Ho WuChian-Ren JengPublished in: BMC veterinary research (2020)
This study suggests that the overexpression of HIF-1α may indicate poor prognosis/overall survival rate in cats with FMGCs. Developing compounds that inhibit HIF-1α may be a potential approach to FMGC treatment.