Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study.

Y H M Krul-PoelP P KoendersR P Steegers-TheunissenE Ten BoekelM M Ter WeeY LouwersP LipsJ S E LavenSuat Simsek

Published in: PloS one (2018)

This study demonstrates that women with PCOS have a significantly lower serum 25(OH)D compared to fertile controls. A compromised vitamin D status in PCOS women is associated with a higher HOMA-IR and an unfavourable lipid profile. Large randomized controlled trials are necessary to explore the causality of this linkage.

Keyphrases

polycystic ovary syndrome
insulin resistance
randomized controlled trial
physical activity
metabolic syndrome
type diabetes
risk factors
gene expression
hiv testing
men who have sex with men