Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study.
Y H M Krul-PoelP P KoendersR P Steegers-TheunissenE Ten BoekelM M Ter WeeY LouwersP LipsJ S E LavenSuat SimsekPublished in: PloS one (2018)
This study demonstrates that women with PCOS have a significantly lower serum 25(OH)D compared to fertile controls. A compromised vitamin D status in PCOS women is associated with a higher HOMA-IR and an unfavourable lipid profile. Large randomized controlled trials are necessary to explore the causality of this linkage.