Alterations in the gut microbiota and their metabolites in human intestinal epithelial cells of patients with colorectal cancer.

Somayeh Jahani-SherafatMasoumeh AzimiradHamideh RaeisiMehdi Azizmohammad LoohaSajjad TavakkoliHamed Ahmadi AmoliSharareh MoghimMohammad Rostami-NejadAbbas YadegarMohammad Reza Zali

Published in: Molecular biology reports (2024)

The influence of bacterial metabolites on inflammation and altered expression of genes in the cell signaling pathways was observed. The findings confirm the role gut microbiota composition and bacterial metabolites as key players in CRC onset and development.

Keyphrases

ms ms
endothelial cells
signaling pathway
poor prognosis
oxidative stress
single cell
cell therapy
stem cells
gene expression
pi k akt
induced pluripotent stem cells
binding protein
epithelial mesenchymal transition
dna methylation
bone marrow