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Spinal protein kinase A and phosphorylated extracellular signal-regulated kinase signaling are involved in the antinociceptive effect of phytohormone abscisic acid in rats.

Mahtab MollashahiRazieh KooshkiSaeed Esmaeili-Mahani
Published in: Arquivos de neuro-psiquiatria (2020)
Overall, i.t. administration of ABA (10 µg/rat) induced analgesia and p-ERK down-expression likely by involving the PKA-dependent mechanism.
Keyphrases
  • protein kinase
  • transcription factor
  • poor prognosis
  • diabetic rats
  • signaling pathway
  • high glucose
  • oxidative stress
  • spinal cord
  • cell proliferation
  • pain management
  • drug induced
  • anti inflammatory
  • long non coding rna