Ketogenic propensity is differentially related to lipid-induced hepatic and peripheral insulin resistance.

Jacob T Mey B Vandagmansar Wagner Silva Dantas K P Belmont Christopher L Axelrod John P Kirwan

Published in: Acta physiologica (Oxford, England) (2023)

This work provides important insight into the role of ketones in human health and suggests that ketone body metabolism is altered at the onset of lipid-induced insulin resistance.

Keyphrases

insulin resistance
human health
high glucose
risk assessment
diabetic rats
adipose tissue
type diabetes
metabolic syndrome
high fat diet
drug induced
skeletal muscle
climate change
fatty acid
endothelial cells
oxidative stress
high fat diet induced
glycemic control