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Mild-to-severe traumatic brain injury in children: altered cytokines reflect severity.

Emer RyanLynne KellyCatherine StaceyDean HuggardEimear DuffDanielle McCollumAnn LeonardGerard BoranDermot R DohertyTurlough BolgerEleanor J Molloy
Published in: Journal of neuroinflammation (2022)
Children with all TBI including mTBI show altered cytokine profiles and altered endotoxin responses. Although cytokines increased in sTBI especially in response to endotoxin, suppressed responses were found in mTBI coupled with persistent immune dysfunction post-injury.
Keyphrases
  • severe traumatic brain injury
  • mild traumatic brain injury
  • traumatic brain injury
  • young adults
  • oxidative stress