Transcatheter or surgical aortic valve implantation: 10-year outcomes of the NOTION trial.
Hans Gustav Hørsted ThyregodTroels Højsgaard JørgensenNikolaj IhlemannDaniel Andreas SteinbrüchelHenrik NissenBo Juel KjeldsenPetur PeturssonOle De BackerPeter Skov OlsenLars SøndergaardPublished in: European heart journal (2024)
In patients with severe AS and lower surgical risk randomized to TAVI or SAVR, the risk of major clinical outcomes was not different 10 years after treatment. The risk of severe bioprosthesis SVD was lower after TAVR compared with SAVR, while the risk of BVF was similar.
Keyphrases
- aortic valve
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic stenosis
- aortic valve replacement
- phase iii
- phase ii
- early onset
- open label
- double blind
- clinical trial
- study protocol
- placebo controlled
- drug induced
- randomized controlled trial
- heart failure
- coronary artery disease
- atrial fibrillation
- metabolic syndrome
- skeletal muscle
- weight loss
- ejection fraction