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Emulation of a randomized controlled trial in ulcerative colitis with US and French claims data: Infliximab with thiopurines compared to infliximab monotherapy.

Julien KirchgesnerRishi J DesaiMaria C SchneeweissLaurent BeaugerieSeoyoung C KimSebastian G Schneeweiss
Published in: Pharmacoepidemiology and drug safety (2021)
RWE results across three large claims databases were consistent with RCT findings. These findings provide support for the use of RWE to assess treatment effectiveness in UC.
Keyphrases
  • ulcerative colitis
  • health insurance
  • combination therapy
  • big data
  • randomized controlled trial
  • systematic review
  • electronic health record
  • machine learning