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In vitro antioxidant and antiproliferative effect of the extracts of Ephedra chilensis K Presl aerial parts.

Marco MelladoMauricio SotoAlejandro MadridIván MontenegroCarlos Jara-GutiérrezJoan VillenaEnrique WernerPatricio GodoyLuis F Aguilar
Published in: BMC complementary and alternative medicine (2019)
The cytotoxic activity and selectivity of the non-polar extracts of E. chilensis for the MCF-7 and PC-3 cell lines could be related to the terpenic compounds and fatty acids of the extracts or to the synergistic effect of all of the compounds in the extracts. These non-polar extracts can be used for the development of new drugs against breast and prostate cancer.
Keyphrases
  • prostate cancer
  • fatty acid
  • oxidative stress
  • radical prostatectomy
  • cancer therapy
  • structural basis