TCL1A-expressing B cells are critical for tertiary lymphoid structure formation and the prognosis of oral squamous cell carcinoma.

Wenqiang XieJinjin LuYichen ChenXi WangHuanzi LuQunxing LiNianqiang JinJiankang HeLingling OuJia NiYuqin ShenLongquan Shao

Published in: Journal of translational medicine (2024)

This study revealed the role of B-cell TCL1A expression in TLS formation and its effect on OSCC prognosis. These findings highlight TCL1A as a novel target for OSCC immunotherapy.

Keyphrases

poor prognosis
single cell