Vertical R1 margins are not always associated with residual neoplasia after endoscopic resection of Barrett's neoplasia: a nationwide cohort with dedicated pathology reassessment.
Laurelle van TilburgEva VerheijSteffi Elisabeth Maria van de VenSanne N van MunsterBas WeustenLorenza Alvarez HerreroWouter B NagengastErik J SchoonAlaa AlkhalafJacques BergmanRoos E PouwLindsey OudijkSybren L MeijerMarnix JansenMichael DoukasArjun Dave KochPublished in: Endoscopy (2024)
Histological evaluation of ER margins appears challenging as 75% of documented R1v cases were confirmed during reassessment. After ER with R1v, 50% of the patients had no residual neoplasia. Endoscopic reassessment 8-12 weeks after ER seems accurately able to detect residual neoplasia and help to determine the most appropriate strategy for patients with R1v.