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Vertical R1 margins are not always associated with residual neoplasia after endoscopic resection of Barrett's neoplasia: a nationwide cohort with dedicated pathology reassessment.

Laurelle van TilburgEva VerheijSteffi Elisabeth Maria van de VenSanne N van MunsterBas WeustenLorenza Alvarez HerreroWouter B NagengastErik J SchoonAlaa AlkhalafJacques BergmanRoos E PouwLindsey OudijkSybren L MeijerMarnix JansenMichael DoukasArjun Dave Koch
Published in: Endoscopy (2024)
Histological evaluation of ER margins appears challenging as 75% of documented R1v cases were confirmed during reassessment. After ER with R1v, 50% of the patients had no residual neoplasia. Endoscopic reassessment 8-12 weeks after ER seems accurately able to detect residual neoplasia and help to determine the most appropriate strategy for patients with R1v.
Keyphrases
  • high grade
  • estrogen receptor
  • ultrasound guided
  • endoplasmic reticulum
  • end stage renal disease
  • breast cancer cells
  • ejection fraction
  • newly diagnosed
  • cross sectional
  • endoscopic submucosal dissection