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Emergency Myelopoiesis Distinguishes Multisystem Inflammatory Syndrome in Children From Pediatric Severe Coronavirus Disease 2019.

Katerina RoznikTemesgen E AndargieT Scott JohnstonOren GordonYi WangNadine Peart AkindeleDeborah PersaudAnnukka A R AntarYukari C ManabeWeiqiang ZhouHongkai JiSean Agbor-EnohAndrew H KarabaElizabeth A ThompsonAndrea L Cox
Published in: The Journal of infectious diseases (2024)
Immune cell signatures of EM combined with elevated innate immune cell-derived cfDNA levels distinguish MIS-C from SAC in children and provide mechanistic insight into dysregulated immunity contributing toward MIS-C, offering potential diagnostic and therapeutic targets.
Keyphrases
  • coronavirus disease
  • innate immune
  • young adults
  • emergency department
  • public health
  • healthcare
  • early onset
  • genome wide
  • case report
  • sars cov
  • risk assessment
  • human health