Potential Role of Selected miRNAs in the Pathogenesis of Autoimmune Thyroid Diseases in Children and Adolescents.

Beata SawickaAnetta SulewskaAgnieszka Kulczyńska-PrzybikFilip Bossowski Maciej DulewiczHanna Borysewicz-SańczykBarbara MroczkoJacek NiklińskiArtur Tadeusz Bossowski

Published in: Biomedicines (2024)

1. The overexpression of the miR-142-5p molecule occurs in children and adolescents with thyroid diseases. 2. Decreased blood levels of miR-15a-5p predispose patients to the formation of focal lesions in the thyroid gland. 3. Identifying a lower expression of the miR-126-3p molecule in the blood of children with GD requires careful follow-up for the development of focal lesions in the thyroid gland and evaluation for their potential malignancy.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
poor prognosis
cell proliferation
young adults
multiple sclerosis
peritoneal dialysis
prognostic factors
risk assessment
clinical evaluation