Fish Oil Diet during Pre-mating, Gestation, and Lactation in Adult Offspring Rats on Cancer Cachexia Prevention.
Sarah Christine Pereira de OliveiraNatália Angelo da Silva MiyagutiSteven Thomas RussellNatália TobarMurilo Vieira GeraldoMaria Cristina Cintra Gomes-MardondesPublished in: Molecular nutrition & food research (2021)
In this experimental model of cachexia, the long-term maternal supplementation is a positive strategy to improve liver function and lipid metabolism, as well as to modify muscle proteins expression in the mTOR pathway and also reduce the 20S muscle proteasome protein, without altering the tumor development and muscle wasting in adult tumor-bearing offspring.
Keyphrases
- skeletal muscle
- high fat diet
- poor prognosis
- childhood cancer
- papillary thyroid
- preterm infants
- binding protein
- physical activity
- insulin resistance
- cell proliferation
- type diabetes
- squamous cell carcinoma
- birth weight
- adipose tissue
- long non coding rna
- metabolic syndrome
- squamous cell
- protein protein
- small molecule
- pregnancy outcomes