Pien Tze Huang Inhibits Proliferation of Colorectal Cancer Cells through Suppressing PNO1 Expression and Activating p53/p21 Signaling Pathway.

Liu-Jing CaoLi-Ya LiuYou-Qin ChenYu-Ying HanLi-Hui WeiMeng-Ying YaoYi FangMei-Zhu WuYing ChengThomas J SferraHui-Xin LiuLi LiJun PengA-Ling Shen

Published in: Chinese journal of integrative medicine (2024)

The mechanism by which PZH induces its CRC anti-proliferative effect is at least in part by regulating the expression of PNO1 and its downstream targets p53 and p21.

Keyphrases

signaling pathway
poor prognosis
pi k akt
binding protein
epithelial mesenchymal transition
induced apoptosis