Sleep-disordered breathing in Australian children with Prader-Willi syndrome following initiation of growth hormone therapy.
Daan CaudriGillian M NixonAleisha NielsenLinda MaiClaire R HafekostNitin KapurChris SetonAndrew TaiGreg BlecherGeoffrey R AmblerPhilip B BergmanKomal Ashokbhai VoraPatricia CrockCharles F VergeElaine ThamYassmin MusthaffaAntony R LaffertyPeter JacobyAndrew C WilsonJennepher Anne DownsCatherine S ChoongPublished in: Journal of paediatrics and child health (2021)
Our findings of a worsening of OSA severity in 13% of children with PWS support current advice to perform polysomnography after GH initiation. Early identification of worsening OSA may prevent severe sequelae in a subgroup of children.