Anti-inflammatory Properties of Tongfeng Li'an Granules in an Acute Gouty Arthritis Rat Model.
Xiang-Pei ZhaoZhaoyang LongHua ZhongRongping LuJuan WeiFengzhen LiZongxi SunPublished in: ACS omega (2024)
This research elucidated the pharmacological mechanisms of TFLA against gouty arthritis, implicating various ingredients, targets, and signaling pathways. Animal experiments confirmed TFLA's efficacy in alleviating inflammation in acute gouty arthritis by modulating Toll-like receptor signaling and NLRP3 expression.
Keyphrases
- toll like receptor
- rheumatoid arthritis
- liver failure
- signaling pathway
- respiratory failure
- anti inflammatory
- nuclear factor
- inflammatory response
- aortic dissection
- drug induced
- oxidative stress
- poor prognosis
- immune response
- pi k akt
- epithelial mesenchymal transition
- extracorporeal membrane oxygenation
- long non coding rna
- nlrp inflammasome
- induced apoptosis