Sulfide oxidation promotes hypoxic angiogenesis and neovascularization.

Roshan KumarVictor VitvitskyProud SethHarrison L HirakiHannah BellAnthony AndrenRashi SinghalBrendon M Baker Costas Andreas LyssiotisYatrik M ShahRuma Banerjee

Published in: bioRxiv : the preprint server for biology (2023)

S synthesis Synergizing with hypoxia, SQOR deficiency induces a reductive shift in the ETC and restricts proliferationSQOR KO mice exhibit lower neovascularization in tumor xenograft and hind limb ischemia models.

Keyphrases

vascular endothelial growth factor
endothelial cells
diabetic retinopathy
high fat diet induced
hydrogen peroxide
replacement therapy
metabolic syndrome
adipose tissue
wild type