Costas Andreas Lyssiotis (Costas A Lysstiotis, Costas Lyssiotis, Costas A Lyssiotis)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 143

Top Venues

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Cancer discovery

Oncogene

This page only lists publications with an associated author ORCID identifier.

Publications

Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Ulka Vaishampayan, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration. bioRxiv : the preprint server for biology (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Ulka Vaishampayan, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration. bioRxiv : the preprint server for biology (2024)
Matthew D Perricone, Costas Andreas Lyssiotis
Fibrotic tumors tune metabolism for immune evasion. Nature cancer (2024)
Annapurna Kuppa, Afnan Alzamrooni, Rachel Lopez, Tahra Suhan, Rajesh Chaudhary, Nicole Collins, Fran Van den Bergh, Riham Abouleisa, Harrison Wang, Tamer Mohamed, Jonathan Satin, Costas Andreas Lyssiotis, Daniel A Beard, Ahmed Abdel-Latif
Inherent Metabolic Adaptations in Adult Spiny Mouse ( Acomys ) Cardiomyocytes Facilitate Enhanced Cardiac Recovery Following Myocardial Infarction. bioRxiv : the preprint server for biology (2024)
Jason Cosgrove, Antoine Marçais, Felix J Hartmann, Andreas Bergthaler, Ivan Zanoni, Mauro Corrado, Leïla Perié, Nina Cabezas-Wallscheid, Philippe Bousso, Theodore Alexandrov, Tammy Kielian, Nuria Martínez-Martín, Christiane A Opitz, Costas Andreas Lyssiotis, Rafael J Argüello, Jan Van den Bossche
A call for accessible tools to unlock single-cell immunometabolism research. Nature metabolism 6 (5) (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration. bioRxiv : the preprint server for biology (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Steven E Pilley, Dominik Awad, Djakim Latumalea, Edgar Esparza, Li Zhang, Xuanyi Shi, Maximilian Unfried, Shuo Wang, Racheal Mulondo, Sriraksha Bharadwaj Kashyap, Darius Moaddeli, Peter Sajjakulnukit, Damien Sutton, Harrison Wong, Aeowynn J Coakley, Gilberto Garcia, Ryo Higuchi-Sanabria, Sophia Liu, Bingfei Yu, William B Tu, Brian Keith Kennedy, Costas Andreas Lyssiotis, Peter J Mullen
A metabolic atlas of mouse aging. bioRxiv : the preprint server for biology (2024)
Jonathan M Alektiar, Mengrou Shan, Megan D Radyk, Li Zhang, Christopher J Halbrook, Lin Lin, Carlos Espinoza, Ivan F Mier, Brooke L Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C Cantley, Jacob L Mueller, Costas Andreas Lyssiotis
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions. PloS one 19 (6) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv : the preprint server for biology (2024)
Brandon Chen, Theophilus M Lynn-Nguyen, Pankaj Jadhav, Benjamin S Halligan, Nicholas J Rossiter, Rachel M Guerra, Sergei Koshkin, Imhoi Koo, Pietro Morlacchi, David A Hanna, Jason Lin, Ruma Banerjee, David J Pagliarini, Andrew D Patterson, Shyamal Mosalaganti, Jonathan Z Sexton, Tito Cali, Costas Andreas Lyssiotis, Yatrik M Shah
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. bioRxiv : the preprint server for biology (2024)
Jason Cosgrove, Antoine Marçais, Felix J Hartmann, Andreas Bergthaler, Ivan Zanoni, Mauro Corrado, Leïla Perié, Nina Cabezas-Wallscheid, Philippe Bousso, Theodore Alexandrov, Tammy Kielian, Nuria Martínez-Martín, Christiane A Opitz, Costas Andreas Lyssiotis, Rafael J Argüello, Jan Van den Bossche
A call for accessible tools to unlock single-cell immunometabolism research. Nature metabolism 6 (5) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Ulka Vaishampayan, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv : the preprint server for biology (2024)
Ajay Kumar, Chenxian Ye, Afia Nkansah, Thomas Decoville, Garrett M Fogo, Peter Sajjakulnukit, Mack B Reynolds, Li Zhang, Osbourne Quaye, Young-Ah Seo, Thomas H Sanderson, Costas Andreas Lyssiotis, Cheong-Hee Chang
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration. bioRxiv : the preprint server for biology (2024)
Ajay Kumar, Chenxian Ye, Afia Nkansah, Thomas Decoville, Garrett M Fogo, Peter Sajjakulnukit, Mack B Reynolds, Li Zhang, Osbourne Quaye, Young-Ah Seo, Thomas H Sanderson, Costas Andreas Lyssiotis, Cheong-Hee Chang
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Asmita Pathak, Sravya Palasalava, Maxon V Knott, Bruno Colon, Erika Ciervo, Yadi Zhou, Jonathan Mitchell, Oriana Teran Pumar, Harrison K A Wong, Li Zhang, Nikola Susic, Khushi Hemendra Shah, Kristen Kay, Diana Chin, Sadie Johnson, Feixiong Cheng, Costas Andreas Lyssiotis, Dionysios C Watson, Michele Ceccarelli, Ashish Shah, Daniel R Wahl, Justin D Lathia, Defne Bayik
γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner. bioRxiv : the preprint server for biology (2024)
Ajay Kumar, Chenxian Ye, Afia Nkansah, Thomas Decoville, Garrett M Fogo, Peter Sajjakulnukit, Mack B Reynolds, Li Zhang, Osbourne Quaye, Young-Ah Seo, Thomas H Sanderson, Costas Andreas Lyssiotis, Cheong-Hee Chang
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Jonathan M Alektiar, Mengrou Shan, Megan D Radyk, Li Zhang, Christopher J Halbrook, Lin Lin, Carlos Espinoza, Ivan F Mier, Brooke L Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C Cantley, Jacob L Mueller, Costas Andreas Lyssiotis
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions. PloS one 19 (6) (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Li Zhang, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival. bioRxiv : the preprint server for biology (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Ulka Vaishampayan, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv : the preprint server for biology (2024)
Ajay Kumar, Chenxian Ye, Afia Nkansah, Thomas Decoville, Garrett M Fogo, Peter Sajjakulnukit, Mack B Reynolds, Li Zhang, Osbourne Quaye, Young-Ah Seo, Thomas H Sanderson, Costas Andreas Lyssiotis, Cheong-Hee Chang
Iron regulates the quiescence of naive CD4 T cells by controlling mitochondria and cellular metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Brandon Chen, Theophilus M Lynn-Nguyen, Pankaj Jadhav, Benjamin S Halligan, Nicholas J Rossiter, Rachel M Guerra, Sergei Koshkin, Imhoi Koo, Pietro Morlacchi, David A Hanna, Jason Lin, Ruma Banerjee, David J Pagliarini, Andrew D Patterson, Shyamal Mosalaganti, Jonathan Z Sexton, Tito Cali, Costas Andreas Lyssiotis, Yatrik M Shah
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. bioRxiv : the preprint server for biology (2024)
Felipe J Núñez, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Claire E Tronrud, Ziwen Zhu, Ayman Taher, Padma Kadiyala, Stephen V Carney, Maria B Garcia-Fabiani, Andrea Comba, Mahmoud S Alghamri, Brandon L McClellan, Syed M Faisal, Zeribe C Nwosu, Hanna S Hong, Tingting Qin, Maureen A Sartor, Mats Ljungman, Shi-Yuan Cheng, Henry D Appelman, Pedro R Lowenstein, Joerg Lahann, Costas Andreas Lyssiotis, Maria G Castro
Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation. bioRxiv : the preprint server for biology (2024)
Jonathan M Alektiar, Mengrou Shan, Megan D Radyk, Li Zhang, Christopher J Halbrook, Lin Lin, Carlos Espinoza, Ivan F Mier, Brooke L Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C Cantley, Jacob L Mueller, Costas Andreas Lyssiotis
Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions. PloS one 19 (6) (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Ulka Vaishampayan, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 121 (15) (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Jason Cosgrove, Antoine Marçais, Felix J Hartmann, Andreas Bergthaler, Ivan Zanoni, Mauro Corrado, Leïla Perié, Nina Cabezas-Wallscheid, Philippe Bousso, Theodore Alexandrov, Tammy Kielian, Nuria Martínez-Martín, Christiane A Opitz, Costas Andreas Lyssiotis, Rafael J Argüello, Jan Van den Bossche
A call for accessible tools to unlock single-cell immunometabolism research. Nature metabolism 6 (5) (2024)
Matthew D Perricone, Costas Andreas Lyssiotis
Fibrotic tumors tune metabolism for immune evasion. Nature cancer 5 (7) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Steven E Pilley, Dominik Awad, Djakim Latumalea, Edgar Esparza, Li Zhang, Xuanyi Shi, Maximilian Unfried, Shuo Wang, Racheal Mulondo, Sriraksha Bharadwaj Kashyap, Darius Moaddeli, Peter Sajjakulnukit, Damien Sutton, Harrison Wong, Aeowynn J Coakley, Gilberto Garcia, Ryo Higuchi-Sanabria, Sophia Liu, Bingfei Yu, William B Tu, Brian Keith Kennedy, Costas Andreas Lyssiotis, Peter J Mullen
A metabolic atlas of mouse aging. bioRxiv : the preprint server for biology (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Brandon Chen, Theophilus M Lynn-Nguyen, Pankaj Jadhav, Benjamin S Halligan, Nicholas J Rossiter, Rachel M Guerra, Sergei Koshkin, Imhoi Koo, Pietro Morlacchi, David A Hanna, Jason Lin, Ruma Banerjee, David J Pagliarini, Andrew D Patterson, Shyamal Mosalaganti, Jonathan Z Sexton, Tito Cali, Costas Andreas Lyssiotis, Yatrik M Shah
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. bioRxiv : the preprint server for biology (2024)
Moloy T Goswami, Eric Weh, Shubha Subramanya, Katherine M Weh, Hima Bindu Durumutla, Heather Hager, Nicholas Miller, Sraboni Chaudhury, Anthony Andren, Peter Sajjakulnukit, Li Zhang, Cagri G Besirli, Costas Andreas Lyssiotis, Thomas J Wubben
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival. bioRxiv : the preprint server for biology (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression. Cancer research communications 4 (5) (2024)
Darren R Heintzman, Rachael C Sinard, Emilie L Fisher, Xiang Ye, Andrew R Patterson, Joel H Elasy, Kelsey Voss, Channing Chi, Ayaka Sugiura, Gabriel J Rodriguez-Garcia, Nowrin U Chowdhury, Emily N Arner, Evan S Krystoviak, Frank M Mason, Yasmine T Toudji, KayLee K Steiner, Wasay Khan, Lana M Olson, Angela L Jones, Hanna S Hong, Lindsay Bass, Katherine L Beier, Wentao Deng, Costas Andreas Lyssiotis, Dawn C Newcomb, Alexander G Bick, W Kimryn Rathmell, John Tanner Wilson, Jeffrey C Rathmell
Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation. Science immunology 9 (99) (2024)
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Stephanie J Miner, Yang Zheng, NamHoon Kim, Victoria Z Zeng, Jasmine P Wisniewski, Siyu Hou, Bailey Jackson, Xuhong Cao, Fengyun Su, Rui Wang, Yu Chang, Bilash Kuila, Subhendu Mukherjee, Sandeep Dukare, Kiran B Aithal, Samiulla D S, Chandrasekhar Abbineni, Costas Andreas Lyssiotis, Abhijit Parolia, Lanbo Xiao, Arul M Chinnaiyan
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv : the preprint server for biology (2024)
Brandon Chen, Theophilus M Lynn-Nguyen, Pankaj Jadhav, Benjamin S Halligan, Nicholas J Rossiter, Rachel M Guerra, Sergei Koshkin, Imhoi Koo, Pietro Morlacchi, David A Hanna, Jason Lin, Ruma Banerjee, David J Pagliarini, Andrew D Patterson, Shyamal Mosalaganti, Jonathan Z Sexton, Tito Cali, Costas Andreas Lyssiotis, Yatrik M Shah
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III. bioRxiv : the preprint server for biology (2024)
Mary M Stangis, Zhengyi Chen, Jimin Min, Sarah E Glass, Jordan O Jackson, Megan D Radyk, Xen Ping Hoi, W Nathaniel Brennen, Ming Yu, Huy Q Dinh, D Borden Lacy, Martha J Shrubsole, Keith Syson Chan, William M Grady, Srinivasan Yegnasubramanian, Costas Andreas Lyssiotis, Anirban Maitra, Richard B Halberg, Neelendu Dey, Ken S Lau
The Hallmarks of Precancer. Cancer discovery 14 (4) (2024)
Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V Crispim, Peter Sajjakulnukit, Maureen A Lyons, Kristine L Cooper, Nadine Hempel, Costas Andreas Lyssiotis, Uma R Chandran, Nathaniel W Snyder, Katherine Marie Aird
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression. Cancer research communications (2024)
Asmita Pathak, Sravya Palasalava, Maxon V Knott, Bruno Colon, Erika Ciervo, Yadi Zhou, Jonathan Mitchell, Oriana Teran Pumar, Harrison K A Wong, Li Zhang, Nikola Susic, Khushi Hemendra Shah, Kristen Kay, Diana Chin, Sadie Johnson, Feixiong Cheng, Costas Andreas Lyssiotis, Dionysios C Watson, Michele Ceccarelli, Ashish Shah, Daniel R Wahl, Justin D Lathia, Defne Bayik
γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner. bioRxiv : the preprint server for biology (2024)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. Proceedings of the National Academy of Sciences of the United States of America 121 (12) (2024)
Jason Cosgrove, Antoine Marçais, Felix J Hartmann, Andreas Bergthaler, Ivan Zanoni, Mauro Corrado, Leïla Perié, Nina Cabezas-Wallscheid, Philippe Bousso, Theodore Alexandrov, Tammy Kielian, Nuria Martínez-Martín, Christiane A Opitz, Costas Andreas Lyssiotis, Rafael J Argüello, Jan Van den Bossche
A call for accessible tools to unlock single-cell immunometabolism research. Nature metabolism (2024)
Ayaka Sugiura, Katherine L Beier, Channing Chi, Darren R Heintzman, Xiang Ye, Melissa M Wolf, Andrew R Patterson, Jacqueline-Yvonne Cephus, Hanna S Hong, Costas Andreas Lyssiotis, Dawn C Newcomb, Jeffrey C Rathmell
Tissue-Specific Dependence of Th1 Cells on the Amino Acid Transporter SLC38A1 in Inflammation. bioRxiv : the preprint server for biology (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene 42 (10) (2023)
David A Hanna, Jutta Diessl, Arkajit Guha, Roshan Kumar, Anthony Andren, Costas Andreas Lyssiotis, Ruma Banerjee
H 2 S preconditioning induces long-lived perturbations in O 2 metabolism. bioRxiv : the preprint server for biology (2023)
Zeribe Chike Nwosu, Matthew H Ward, Peter Sajjakulnukit, Pawan Poudel, Chanthirika Ragulan, Steven Kasperek, Megan Radyk, Damien Sutton, Rosa E Menjivar, Anthony Andren, Juan J Apiz-Saab, Zachary Tolstyka, Kristee Brown, Ho-Joon Lee, Lindsey N Dzierozynski, Xi He, Hari Ps, Julia M Ugras, Gift Nyamundanda, Li Zhang, Christopher J Halbrook, Eileen S Carpenter, Jiaqi Shi, Leah P Shriver, Gary J Patti, Alexander Muir, Marina Pasca di Magliano, Anguraj Sadanandam, Costas Andreas Lyssiotis
Uridine-derived ribose fuels glucose-restricted pancreatic cancer. Nature (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene (2023)
Eric C Martens, Gabriel Vasconcelos Pereira, Marie Boudaud, Mathis Wolter, Celeste Alexander, Alessandro De Sciscio, Erica T Grant, Bruno Caetano Trindade, Nicholas Pudlo, Shaleni Singh, Austin Campbell, Mengrou Shan, Li Zhang, Stéphanie Willieme, Kwi Kim, Trisha Denike-Duval, Marijana Basic, Thomas M Schmidt, Lucy Kennedy, Costas Andreas Lyssiotis, Grace Chen, Kathryn Eaton, Mahesh S Desai
Unravelling specific diet and gut microbial contributions to inflammatory bowel disease. Research square (2023)
Dionysios C Watson, Defne Bayik, Simon Storevik, Shannon Sherwin Moreino, Samuel A Sprowls, Jianhua Han, Mina Thue Augustsson, Adam Lauko, Palavalasa Sravya, Gro Vatne Røsland, Katie Troike, Karl Johan Tronstad, Sabrina Wang, Katharina Sarnow, Kristen Kay, Taral R Lunavat, Daniel J Silver, Sahil Dayal, Justin Vareecal Joseph, Erin Mulkearns-Hubert, Lars Andreas Rømo Ystaas, Gauravi M Deshpande, Joris Guyon, Yadi Zhou, Capucine R Magaut, Juliana Seder, Laura Neises, Sarah E Williford, Johannes Meiser, Andrew J Scott, Peter Sajjakulnukit, Jason A Mears, Rolf Bjerkvig, Abhishek Chakraborty, Thomas Daubon, Feixiong Cheng, Costas Andreas Lyssiotis, Daniel R Wahl, Anita B Hjelmeland, Jubayer A Hossain, Hrvoje Miletic, Justin D Lathia
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. Nature cancer (2023)
Weihua Zhou, Zitong Zhao, Angelica Lin, John Yang, Jie Xu, Wilder-Romans Kari, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer Speth, Natalie Walker, Andrew J Scott, Ayesha U Kothari, Yangyang Yao, Erik R Peterson, Navyateja Korimerla, Christian K Werner, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M Obrien, Ameer L Elaimy, Sean P Ferris, Shuang G Zhao, Jann N Sarkaria, Balázs Győrffy, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A Morgan, Theodore S Lawrence, Costas Andreas Lyssiotis, Marc Peters-Golden, Yatrik M Shah, Daniel R Wahl
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. bioRxiv : the preprint server for biology (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene (2023)
Roshan Kumar, Victor Vitvitsky, Proud Seth, Harrison L Hiraki, Hannah Bell, Anthony Andren, Rashi Singhal, Brendon M Baker, Costas Andreas Lyssiotis, Yatrik M Shah, Ruma Banerjee
Sulfide oxidation promotes hypoxic angiogenesis and neovascularization. bioRxiv : the preprint server for biology (2023)
Ziheng Chen, I-Lin Ho, Melinda Soeung, Er-Yen Yen, Jintan Liu, Liang Yan, Johnathon L Rose, Sanjana Srinivasan, Shan Jiang, Q Edward Chang, Ningping Feng, Jason P Gay, Qi Wang, Jing Wang, Philip L Lorenzi, Lucas J Veillon, Bo Wei, John N Weinstein, Angela K Deem, Sisi Gao, Giannicola Genovese, Andrea Viale, Wantong Yao, Costas Andreas Lyssiotis, Joseph R Marszalek, Giulio F Draetta, Haoqiang Ying
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis. Nature communications 14 (1) (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Weihua Zhou, Zitong Zhao, Angelica Lin, John Yang, Jie Xu, Wilder-Romans Kari, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer Speth, Natalie Walker, Andrew J Scott, Ayesha U Kothari, Yangyang Yao, Erik R Peterson, Navyateja Korimerla, Christian K Werner, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M Obrien, Ameer L Elaimy, Sean P Ferris, Shuang G Zhao, Jann N Sarkaria, Balázs Győrffy, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A Morgan, Theodore S Lawrence, Costas Andreas Lyssiotis, Marc Peters-Golden, Yatrik M Shah, Daniel R Wahl
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. bioRxiv : the preprint server for biology (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Weihua Zhou, Zitong Zhao, Angelica Lin, John Yang, Jie Xu, Wilder-Romans Kari, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer Speth, Natalie Walker, Andrew J Scott, Ayesha U Kothari, Yangyang Yao, Erik R Peterson, Navyateja Korimerla, Christian K Werner, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M Obrien, Ameer L Elaimy, Sean P Ferris, Shuang G Zhao, Jann N Sarkaria, Balázs Győrffy, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A Morgan, Theodore S Lawrence, Costas Andreas Lyssiotis, Marc Peters-Golden, Yatrik M Shah, Daniel R Wahl
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. bioRxiv : the preprint server for biology (2023)
Hans Carlo Maurer, Álvaro Curiel-García, Sam Holmstrom, Pasquale Laise, Carmine F Palermo, Steven A Sastra, Anthony Andren, Zhang Li, Tessa LeLarge, Irina R Sagalovskiy, Daniel R Ross, Vilma Rosario, Kate Lu, Ethan Ferraiuolo, Nicholas Spinosa, Winston Wong, Kaitlin Shaw, John A Chabot, Jeanine M Genkinger, Hanina Hibshoosh, Gulam A Manji, Alina Iuga, Roland M Schmid, Michael A Badgley, Kristen Johnson, Andrea Califano, Costas Andreas Lyssiotis, Kenneth P Olive
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer. bioRxiv : the preprint server for biology (2023)
Rosa Elena Menjivar, Zeribe C Nwosu, Wenting Du, Katelyn L Donahue, Hanna S Hong, Carlos Espinoza, Kristee Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima, Allison C Bischoff, Padma Kadiyala, Daniel J Salas-Escabillas, Howard C Crawford, Filip Bednar, Eileen S Carpenter, Yaqing Zhang, Christopher J Halbrook, Costas Andreas Lyssiotis, Marina Pasca Di Magliano
Arginase 1 is a key driver of immune suppression in pancreatic cancer. eLife 12 (2023)
Rosa Elena Menjivar, Zeribe C Nwosu, Wenting Du, Katelyn L Donahue, Hanna S Hong, Carlos Espinoza, Kristee Brown, Ashley Velez-Delgado, Wei Yan, Fatima Lima, Allison C Bischoff, Padma Kadiyala, Daniel J Salas-Escabillas, Howard C Crawford, Filip Bednar, Eileen S Carpenter, Yaqing Zhang, Christopher J Halbrook, Costas Andreas Lyssiotis, Marina Pasca Di Magliano
Arginase 1 is a key driver of immune suppression in pancreatic cancer. eLife 12 (2023)
Mary M Riwes, Jonathan L Golob, John Magenau, Mengrou Shan, Gregory Dick, Thomas Braun, Thomas M Schmidt, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung Won Choi, Gregory Yanik, Marcus Geer, Ethan Hillman, Costas Andreas Lyssiotis, Muneesh Tewari, Pavan Reddy
Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation. Nature medicine (2023)
Weihua Zhou, Zitong Zhao, Angelica Lin, John Z Yang, Jie Xu, Kari Wilder-Romans, Annabel Yang, Jing Li, Sumeet Solanki, Jennifer M Speth, Natalie Walker, Andrew J Scott, Lu Wang, Bo Wen, Anthony Andren, Li Zhang, Ayesha U Kothari, Yangyang Yao, Erik R Peterson, Navyateja Korimerla, Christian K Werner, Alexander Ullrich, Jessica Liang, Janna Jacobson, Sravya Palavalasa, Alexandra M O'Brien, Ameer L Elaimy, Sean P Ferris, Shuang G Zhao, Jann N Sarkaria, Gyorffy Balazs, Shuqun Zhang, Wajd N Al-Holou, Yoshie Umemura, Meredith A Morgan, Theodore S Lawrence, Costas Andreas Lyssiotis, Marc Peters-Golden, Yatrik M Shah, Daniel R Wahl
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. Cancer discovery (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M Waszak, Stefan R Sweha, Mateus Mota, Matthew Pun, Akash Deogharkar, Chan Chung, Rohinton S Tarapore, Samuel Ramage, Andrew S Chi, Patrick Yung Wen, Isabel C Arrillaga-Romany, Tracy T Batchelor, Nicholas A Butowski, Ashley L Sumrall, Nicole A Shonka, Rebecca A Harrison, John de Groot, Minesh P Mehta, Matthew D Hall, Doured Daghistani, Timothy F Cloughesy, Benjamin M Ellingson, Kevin Beccaria, Pascale Varlet, Michelle M Kim, Yoshie Umemura, Hugh J L Garton, Andrea T Flynn, Jonathan Schwartz, Rajan Jain, Maureen Kachman, Heidi Baum, Charles F Burant, Sophie L Mottl, Rodrigo T Cartaxo, Vishal John, Dana Messinger, Tingting Qin, Erik R Peterson, Peter Sajjakulnukit, Karthik Ravi, Alyssa Waugh, Dustin Walling, Yujie Ding, Ziyun Xia, Anna A Schwendeman, Debra Hawes, Fusheng Yang, Alexander R Judkins, Daniel R Wahl, Costas Andreas Lyssiotis, Daniel de la Nava, Marta Marija Alonso, Augustine Eze, Jasper Spitzer, Susanne Viktoria Schmidt, Ryan J Duchatel, Matthew D Dun, Jason E Cain, Li Jiang, Sylwia A Stopka, Gerard Baquer, Michael S Regan, Mariella G Filbin, Nathalie Y R Agar, Lili Zhao, Chandan Kumar-Sinha, Rajen J Mody, Arul M Chinnaiyan, Ryo Kurokawa, Sriram Venneti, Viveka N Yadav, Jacques Grill, Cassie N Kline, Romain Mueller, Adam C Resnick, Javad Nazarian, Joshua E Allen, Yazmin Odia, Sharon L Gardner, Carl J Koschmann
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways. Cancer discovery (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene 42 (10) (2023)
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel Andrew Kerk, Costas Andreas Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J Weiss
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. The Journal of cell biology 222 (4) (2023)
Zeribe Chike Nwosu, Mun Gu Song, Marina Pasca di Magliano, Costas Andreas Lyssiotis, Sung Eun Kim
Nutrient transporters: connecting cancer metabolism to therapeutic opportunities. Oncogene 42 (10) (2023)
Dionysios C Watson, Defne Bayik, Simon Storevik, Shannon Sherwin Moreino, Samuel A Sprowls, Jianhua Han, Mina Thue Augustsson, Adam Lauko, Palavalasa Sravya, Gro Vatne Røsland, Katie Troike, Karl Johan Tronstad, Sabrina Wang, Katharina Sarnow, Kristen Kay, Taral R Lunavat, Daniel J Silver, Sahil Dayal, Justin Vareecal Joseph, Erin Mulkearns-Hubert, Lars Andreas Rømo Ystaas, Gauravi M Deshpande, Joris Guyon, Yadi Zhou, Capucine R Magaut, Juliana Seder, Laura Neises, Sarah E Williford, Johannes Meiser, Andrew J Scott, Peter Sajjakulnukit, Jason A Mears, Rolf Bjerkvig, Abhishek Chakraborty, Thomas Daubon, Feixiong Cheng, Costas Andreas Lyssiotis, Daniel R Wahl, Anita B Hjelmeland, Jubayer A Hossain, Hrvoje Miletic, Justin D Lathia
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. Nature cancer (2023)
Matthew H Ward, Zeribe C Nwosu, Costas Andreas Lyssiotis
Uridine: as sweet as sugar for some cells? Cell research (2023)
Mack B Reynolds, Hanna S Hong, Britton C Michmerhuizen, Anna-Lisa E Lawrence, Li Zhang, Christian Lood, Costas Andreas Lyssiotis, Basel H Abuaita, Mary X D O'Riordan
Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation. Science advances 9 (5) (2023)
Zeribe Chike Nwosu, Matthew H Ward, Peter Sajjakulnukit, Pawan Poudel, Chanthirika Ragulan, Steven Kasperek, Megan Radyk, Damien Sutton, Rosa E Menjivar, Anthony Andren, Juan J Apiz-Saab, Zachary Tolstyka, Kristee Brown, Ho-Joon Lee, Lindsey N Dzierozynski, Xi He, Hari Ps, Julia M Ugras, Gift Nyamundanda, Li Zhang, Christopher J Halbrook, Eileen S Carpenter, Jiaqi Shi, Leah P Shriver, Gary J Patti, Alexander Muir, Marina Pasca di Magliano, Anguraj Sadanandam, Costas Andreas Lyssiotis
Uridine-derived ribose fuels glucose-restricted pancreatic cancer. Nature (2023)
Hanna S Hong, Nneka E Mbah, Mengrou Shan, Kristen Loesel, Lin Lin, Peter Sajjakulnukit, Luis O Correa, Anthony Andren, Jason Lin, Atsushi Hayashi, Brian R Magnuson, Judy Chen, Zhaoheng Li, Yuying Xie, Li Zhang, Daniel R Goldstein, Shannon Ann Carty, Yu Leo Lei, Anthony W Opipari, Rafael Jose Argüello, Ilona Kryczek, Nobuhiko Kamada, Weiping Zou, Luigi Franchi, Costas Andreas Lyssiotis
OXPHOS promotes apoptotic resistance and cellular persistence in T H 17 cells in the periphery and tumor microenvironment. Science immunology 7 (77) (2022)
Carmen Mirabelli, Melissa K Jones, Vivienne L Young, Abimbola O Kolawole, Irene Owusu, Mengrou Shan, Basel Abuaita, Holly Turula, Jose G Trevino, Irina Grigorova, Steven K Lundy, Costas Andreas Lyssiotis, Vernon K Ward, Stephanie M Karst, Christiane E Wobus
Human Norovirus Triggers Primary B Cell Immune Activation In Vitro . mBio 13 (2) (2022)
Seth Boyer, Ho-Joon Lee, Nina Steele, Li Zhang, Peter Sajjakulnukit, Anthony Andren, Matthew H Ward, Rima Singh, Venkatesha Basrur, Yaqing Zhang, Alexey I Nesvizhskii, Marina Pasca di Magliano, Christopher J Halbrook, Costas Andreas Lyssiotis
Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway. eLife 11 (2022)
Johanna M Buschhaus, Shrila Rajendran, Brock A Humphries, Alyssa C Cutter, Ayşe J Muñiz, Nicholas G Ciavattone, Alexander M Buschhaus, Tatiana Cañeque, Zeribe C Nwosu, Debashis Sahoo, Avinash S Bevoor, Yatrik M Shah, Costas Andreas Lyssiotis, Pradipta Ghosh, Max S Wicha, Raphaël Rodriguez, Gary D Luker
Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer. Oncogene 41 (29) (2022)

Costas Andreas Lyssiotis.css-eqlu8i{font-size:small;padding-left:4px;} (Costas A Lysstiotis, Costas Lyssiotis, Costas A Lyssiotis)

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Costas Andreas Lyssiotis (Costas A Lysstiotis, Costas Lyssiotis, Costas A Lyssiotis)