Combined Histologic and Endoscopic Endpoints at Post-induction Lack Additional Prognostic Value Compared to Endoscopic Improvement Alone in Ulcerative Colitis: A Post-hoc Analysis of the VARSITY study.

In this post-hoc analysis, at post-induction, HEMI did not demonstrate additional prognostic value in predicting one-year outcomes over EI. However, HEMI was associated with lower clinical disease activity at post-induction and at one-year compared to endoscopic or histologic outcomes in isolation.