Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation.

Jie WuLing GuoXiaoran QiuYong RenFeifei LiWei CuiShao-Jiang Song

Published in: British journal of cancer (2020)

Our data suggest that DHCR24-mediated cholesterol metabolism might be an effective therapeutic strategy in HCC, and natural product GD might be a promising agent for HCC therapy.

Keyphrases

low density lipoprotein
cell migration
stem cells
fatty acid
machine learning
bone marrow
data analysis