Peripheral Inflammation Is Associated with Dopaminergic Degeneration in Parkinson's Disease.
Pablo MirMiguel Ángel Labrador-EspinosaDaniel Macías-GarcíaSilvia JesúsBelén Benítez ZamoraPaula Fernández-RodríguezAstrid D Adarmes-GómezMaría Isabel Reina CastilloSandra Castro-LabradorJesus Silva-RodriguezFátima CarrilloDavid García SolísMichel J GrothePablo MirPublished in: Movement disorders : official journal of the Movement Disorder Society (2023)
Our findings across two independent cohorts suggest a relationship between systemic inflammation and dopaminergic degeneration in patients with PD. This relationship was mainly driven by the lymphocyte count. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.