Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation.

Huan DengQingqing HangDijian ShenYibi ZhangMing Chen

Published in: Cancer cell international (2021)

Our study revealed that survival-related hub genes closely correlated with the initiation and progression of LUAD. Furthermore, CHRDL1 and SPARCL1 are potential therapeutic and prognostic indicators of LUAD.

Keyphrases

poor prognosis
long non coding rna
bioinformatics analysis
genome wide
single cell
transcription factor
dna methylation
network analysis
genome wide identification