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Evaluating the Phenotypic Patterns of Post-Traumatic Headache: A Systematic Review of Military Personnel.

Hannah S LyonsMatilde SassaniMark ThallerAndreas YiangouOlivia GrechMiss Susan P MollanDuncan R WilsonSamuel J E LucasJames L MitchellAdrian C WilliamsAlexandra Jean Sinclair
Published in: Military medicine (2024)
This systematic review demonstrated that PTH in the military population frequently exhibit migraine-like features. Tension-type headache and trigeminal autonomic cephalalgias also occur, although less commonly reported. Sub-phenotyping PTH may be important for initiating effective treatment since different phenotypes may respond differently to medications. The study populations analyzed in this systematic review display heterogeneity, underscoring the necessity for additional research features, more stringent criteria and comprehensive recording of baseline characteristics. Characterizing headaches following injury is crucial for an accurate diagnosis to enable effective management and rehabilitation planning for our armed forces.
Keyphrases
  • systematic review
  • meta analyses
  • high throughput
  • randomized controlled trial
  • high resolution
  • posttraumatic stress disorder
  • neuropathic pain
  • spinal cord
  • mass spectrometry
  • smoking cessation