Influence of gender and sexual hormones on outcomes after pituitary surgery: a systematic review and meta-analysis.
Sven TheilerSaskia HegetschweilerVictor E StaartjesAntonio SpinelloGiovanna BrandiLuca RegliCarlo SerraPublished in: Acta neurochirurgica (2023)
There was a significantly higher rate of postoperative DI in female patients after endoscopic or microscopic transsphenoidal PA surgery, and although there was some data in isolated studies suggesting influence of gender on postoperative biochemical remission, rate of GTR, and preoperative prolactin levels, these findings could not be confirmed in this meta-analysis and demonstrated no statistically significant effect. Further research is needed and future studies concerning PA surgery should report their data by gender or sexual hormones and ideally further assess their impact on PA surgery.
Keyphrases
- minimally invasive
- coronary artery bypass
- mental health
- systematic review
- patients undergoing
- surgical site infection
- case control
- electronic health record
- newly diagnosed
- ejection fraction
- randomized controlled trial
- prognostic factors
- percutaneous coronary intervention
- big data
- pseudomonas aeruginosa
- coronary artery disease
- staphylococcus aureus
- machine learning
- meta analyses
- biofilm formation