Independent and joint correlation of PNPLA3 I148M and TM6SF2 E167K variants with the risk of coronary heart disease in patients with non-alcoholic fatty liver disease.

Jian-Ting WuShou-Sheng LiuXiang-Jun XieQun LiuYong-Ning XinShi-Ying Xuan

Published in: Lipids in health and disease (2020)

There was a joint protective correlation of PNPLA3 I148M and TM6SF2 E167K variants with the developmental risk of CHD in NAFLD patients. PNPLA3 I148M and TM6SF2 E167K variants might correlated with the decreased risk of CHD in NAFLD patients by associated with the reduced serum lipid levels.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
copy number
prognostic factors
patient reported outcomes
genome wide
fatty acid