Remote electrical neuromodulation to treat children and adolescents with migraine in the emergency department: A randomized double-dummy pilot trial.
Serena Laura OrrJonathan KuziekSamina AliEva AndersonKathryn A BirnieAndrew D HersheyPrachi KhannaAdam KirtonTolulope SajobiStephen B FreedmanPublished in: Headache (2024)
We demonstrated the feasibility and acceptability of our trial protocol and of using REN to treat youth presenting to the ED with migraine. The parallel-group design generated a higher recruitment rate than the crossover design. Our preliminary efficacy and safety data suggest that REN could be non-inferior to typical care, but we were not powered for these outcomes. Further research on REN's use in the ED setting is warranted.
Keyphrases
- emergency department
- healthcare
- randomized controlled trial
- mental health
- study protocol
- physical activity
- clinical trial
- quality improvement
- electronic health record
- case report
- phase ii
- metabolic syndrome
- type diabetes
- pain management
- machine learning
- molecularly imprinted
- skeletal muscle
- adipose tissue
- deep learning
- artificial intelligence
- weight loss
- affordable care act