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Expression of lncRNA MALAT1 through miR-144-3p in Osteoporotic Tibial Fracture Rats and Its Effect on Osteogenic Differentiation of BMSC under Traction.

Shiyong LingTao XuJingchuan SunChen YanBo LvHua WangHong ZhaoKai Huang
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
In the OP rat model with the tibial fracture, the expression of MALAT1 is upregulated and that of miR-144-3p is downregulated. MALAT1 has a targeting relationship with miR-144-3p, and downregulation of MALAT1 and upregulation of miR-144-3p can promote the osteogenic differentiation of BMSC under traction.
Keyphrases
  • poor prognosis
  • total knee arthroplasty
  • long non coding rna
  • signaling pathway
  • binding protein
  • hip fracture
  • cancer therapy
  • anterior cruciate ligament reconstruction