Role of Circ-ITCH Gene Polymorphisms and Its Expression in Breast Cancer Susceptibility and Prognosis.

Sara F Saadawy Nermin Raafat Walaa M SamyAhmed RaafatAliaa Talaat

Published in: Diagnostics (Basel, Switzerland) (2023)

Our research showed that the rs10485505 polymorphism (T allele) and the rs4911154 polymorphism (A allele) are associated with the risk and prognosis of BC. This finding may be due to the effect on the level of circ-ITCH mRNA expression in BC tissues as well as the level of β-catenin in BC patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
poor prognosis
cell proliferation
prognostic factors
peritoneal dialysis
atopic dermatitis
binding protein
patient reported