Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita.

Ester CoutinhoLeslie JacobsonAnthony ShockBryan SmithAnthony Christopher VernonAngela Vincent

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

FcRn blockade is a promising therapeutic strategy to prevent the occurrence of AMC and other human maternal autoantibody-related diseases in the offspring.

Keyphrases

mouse model
birth weight
endothelial cells
pregnancy outcomes
risk assessment
high fat diet
induced pluripotent stem cells
high throughput
pluripotent stem cells
gestational age
pregnant women
type diabetes
weight gain
adipose tissue
real time pcr
metabolic syndrome
physical activity