Login / Signup

Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options.

Gao Jing OngThanh Ha NguyenSven Y SurikowChukwudiebube N Ajaero
Published in: Expert review of clinical pharmacology (2022)
-adrenoceptor stimulation, increased responsiveness to NO and triggering of activation of poly(ADP-ribose) polymerase (PARP). In theory, interruption of this 'cascade' represents a logical approach to improving both symptomatic status and survival post TTS. Currently, there is some evidence supporting routine long-term treatment post TTS with either ACE inhibitors or angiotensin receptor antagonists, both to reduce risk of recurrence and to improve survival. Results of ongoing controlled clinical trials are awaited.
Keyphrases