Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer.

Jun-Chieh J TsayBenjamin G WuMichelle H BadriJose C ClementeNan ShenPeter MeynYonghua LiTing-An YieTenzin LhakhangEvan OlsenVivek MurthyGaetane MichaudImran SulaimanAristotelis TsirigosAdriana HeguyHarvey PassMichael D WeidenWilliam N RomDaniel H StermanRichard BonneauMartin J BlaserLeopoldo N Segal

Published in: American journal of respiratory and critical care medicine (2019)

The data presented here show that several transcriptomic signatures previously identified as relevant to lung cancer pathogenesis are associated with enrichment of the lower airway microbiota with oral commensals.

Keyphrases

electronic health record
cell proliferation
poor prognosis
single cell
big data
signaling pathway
genome wide
machine learning
long non coding rna