Effect of surgery versus chemotherapy in pancreatic cancer patients: a target trial emulation.
Jakob KirkegårdCharles GaberUffe Heide-JørgensenClaus Wilki FristrupJennifer L LundDeirdre Cronin-FentonFrank Viborg MortensenPublished in: Journal of the National Cancer Institute (2024)
Surgery was superior to chemotherapy in achieving long-term survival for pancreatic cancer. The difference comparing surgery and chemotherapy was substantially smaller when using the clone-censor-weight approach than conventional survival analysis.
Keyphrases
- minimally invasive
- coronary artery bypass
- locally advanced
- surgical site infection
- end stage renal disease
- newly diagnosed
- squamous cell carcinoma
- body mass index
- study protocol
- physical activity
- prognostic factors
- weight loss
- randomized controlled trial
- radiation therapy
- phase iii
- body weight
- patient reported
- placebo controlled