Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance.
Stephen V CarneyKaushik BanerjeeAnzar A MujeebBrandon ZhuSantiago HaaseMaría Luisa VarelaPadma KadiyalaClaire E TronrudZiwen ZhuDevarshi MukherjiPreethi GorlaYilun SunRebecca TagettFelipe J NúñezMaowu LuoMaowu LuoMats LjungmanYayuan LiuZiyun XiaAnna A SchwendemanTingting QinMaureen A SartorJoseph F CostelloDaniel P CahillPedro R LowensteinMaria Graciela CastroPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
These findings indicate the impact of ZMYND8 in the maintenance of genomic integrity and repair of IR-induced DNA damage in mIDH1 glioma.