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Donor acquired visceral leishmaniasis following liver transplantation.

Amritpal DhaliwalAbhishek ChauhanDinesh AggarwalPretin DavdaMiruna DavidRasoul Amel-KashipazRachel BrownMartin DedicoatFiona ClarkTahir ShahAhmed Mohamed ElsharkawyInes Ushiro-LumbPeter ChiodiniOmar El-SherifMatthew ArmstrongJames W Ferguson
Published in: Frontline gastroenterology (2021)
Patients who undergo solid organ transplantation are at risk of opportunistic infection associated with immunosuppression. We report a case of confirmed donor derived visceral leishmaniasis (VL), in a patient following liver transplantation causing fever and pancytopenia. The diagnosis was confirmed by bone marrow biopsy, with confirmed positive donor serology, with no other route of transmission. To our knowledge, this is the first case report in the United Kingdom and Europe, of confirmed organ donor transmission of VL. This case report highlights an important consideration of donor derived infections, in the context of solid organ transplantation.
Keyphrases
  • case report
  • bone marrow
  • healthcare
  • mesenchymal stem cells
  • cell therapy
  • cross sectional