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Role of aldosterone in the activation of primary mice hepatic stellate cell and liver fibrosis via NLRP3 inflammasome.

Yang LiYijie ZhangTingting ChenYun HuangYan ZhangShiyu GengXu Li
Published in: Journal of gastroenterology and hepatology (2020)
Aldo promotes the activation of HSCs and liver fibrosis through NLRP3 inflammasome relative pathways. Intervention of aldo and NLRP3 inflammasome-related pathways may provide a promising strategy for treatment of liver fibrosis.
Keyphrases
  • liver fibrosis
  • nlrp inflammasome
  • randomized controlled trial
  • single cell
  • type diabetes
  • adipose tissue
  • combination therapy
  • replacement therapy