A spontaneously metastatic model of bladder cancer: imaging characterization.

James L Tatum Joseph D Kalen Paula M Jacobs Lilia V Ileva Lisa A Riffle Melinda G Hollingshead James H Doroshow

Published in: Journal of translational medicine (2019)

PDX BL0293F is a reliable visceral organ (liver) metastatic model with high penetrance in both non-aggravated and post excisional situations, providing a reliable window for therapy intervention prior to required excision of the xenograft. The imaging characteristics of this model are highly favorable for non-clinical research studies of metastatic disease when used in conjunction with non-contrast T2 weighted MRI.

Keyphrases

squamous cell carcinoma
small cell lung cancer
high resolution
contrast enhanced
magnetic resonance
randomized controlled trial
stem cells
computed tomography
insulin resistance
mass spectrometry
skeletal muscle
adipose tissue
mesenchymal stem cells
cell therapy
case control