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Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein.

Michel A StruweBernd ClementAxel J Scheidig
Published in: Hepatology communications (2022)
A study recently published in Hepatology Communications provided insights into a variant of MTARC1 protein, which conveys protection against liver disease. Here, we report a crystal structure of the variant protein at near-atomic resolution and compare it to the structure of the wildtype protein.
Keyphrases
  • protein protein
  • amino acid
  • binding protein
  • endothelial cells
  • randomized controlled trial
  • systematic review
  • small molecule