Xenon-129 MRI detects ventilation deficits in paediatric stem cell transplant patients unable to perform spirometry.
Laura L WalkupKasiani MyersJavier El-BietarAdam NelsonMatthew M WillmeringMichael GrimleyStella M DaviesChristopher ToweJason C WoodsPublished in: The European respiratory journal (2019)
Lung ventilation deficits were detected using hyperpolarised 129Xe gas MRI in asymptomatic paediatric HSCT patients and in a subgroup who were unable to perform reliable spirometry. 129Xe MRI provides a reliable imaging-based assessment of pulmonary involvement in this potentially difficult to diagnose paediatric population.
Keyphrases
- end stage renal disease
- stem cells
- ejection fraction
- magnetic resonance imaging
- newly diagnosed
- chronic kidney disease
- intensive care unit
- emergency department
- traumatic brain injury
- contrast enhanced
- prognostic factors
- peritoneal dialysis
- high resolution
- pulmonary hypertension
- diffusion weighted imaging
- patient reported outcomes
- randomized controlled trial
- clinical trial
- magnetic resonance
- bone marrow
- mesenchymal stem cells
- open label