Heterogeneity of GNAQ/11 mutation inversely correlates with the metastatic rate in uveal melanoma.
Chen LiangLan Ya PengMing ZouXuemei ChenYingying ChenHou ChenLirong XiaoNaihong YanJunjun ZhangQing ZhaoXi HuangPublished in: The British journal of ophthalmology (2019)
The mutation ratio of GNAQ/11 in UM was quite variable. The tumour with heterogeneous mutation of GNAQ/11 is more likely to develop a poor prognosis than that with homogeneous mutation of GNAQ/11.