Anti-tuberculosis effect of isoniazid scales accurately from zebrafish to humans.

Rob Christiaan van Wijk Wanbin HuSharka M DijkemaDirk-Jan van den BergJeremy LiuRida BahiFons J Verbeek Ulrika S H Simonsson Herman P SpainkPiet H van der GraafElke H J Krekels

Published in: British journal of pharmacology (2020)

This proof of concept study confirmed the potential of zebrafish larvae as tuberculosis disease models in translational pharmacology and contributes to innovative anti-tuberculosis drug development, which is very clearly needed.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
hiv aids
adverse drug
emergency department
risk assessment
zika virus
human health
aedes aegypti