Elke H J Krekels

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 17

Top Venues

Drugs

CPT: pharmacometrics & systems pharmacology

Clinical pharmacokinetics

British journal of clinical pharmacology

Leiden University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Leiden University Jun 01 2014

Netherlands

Assistant Professor :: Systems Biomedicine and Pharmacology

Uppsala University Aug 01 2012 - Aug 31 2014

Sweden

Post Doctoral researcher :: Pharmaceutical Biosciences

Leiden University Mar 01 2007 - Jul 31 2012

Netherlands

PhD student :: Pharmacology

Publications

Tan Zhang, Elke H J Krekels, Cornelis Smit, Eric P A van Dongen, Roger J M Brüggemann, Catherijne A J Knibbe
How to Dose Vancomycin in Overweight and Obese Patients with Varying Renal (Dys)function in the Novel Era of AUC 400-600 mg·h/L-Targeted Dosing. Clinical pharmacokinetics (2023)
Lu Chen, Elke H J Krekels, Anne R Heijnen, Catherijne A J Knibbe, Roger J M Brüggemann
An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers. Drugs 83 (1) (2023)
Lu Chen, Elke H J Krekels, Anne R Heijnen, Catherijne A J Knibbe, Roger J M Brüggemann
An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers. Drugs 83 (1) (2023)
Lu Chen, Elke H J Krekels, Anne R Heijnen, Catherijne A J Knibbe, Roger J M Brüggemann
An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers. Drugs (2023)
Tan Zhang, Cornelis Smit, Catherine M T Sherwin, Catherijne A J Knibbe, Elke H J Krekels
Vancomycin Clearance in Obese Adults is not Predictive of Clearance in Obese Adolescents. Clinical pharmacokinetics (2023)
Lu Chen, Elke H J Krekels, Anne R Heijnen, Catherijne A J Knibbe, Roger J M Brüggemann
An Integrated Population Pharmacokinetic Analysis for Posaconazole Oral Suspension, Delayed-Release Tablet, and Intravenous Infusion in Healthy Volunteers. Drugs 83 (1) (2023)
Koen P van Rhee, Cornelis Smit, Roeland E Wasmann, Paul D van der Linden, Marinus J Wiezer, Eric P A Van Dongen, Elke H J Krekels, Roger J M Brüggemann, Catherijne A J Knibbe
Ciprofloxacin Pharmacokinetics After Oral and Intravenous Administration in (Morbidly) Obese and Non-obese Individuals: A Prospective Clinical Study. Clinical pharmacokinetics 61 (8) (2022)
Feiyan Liu, Linda B S Aulin, Tingjie Guo, Elke H J Krekels, Matthijs Moerland, Piet H van der Graaf, Johan G C van Hasselt
Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations. British journal of clinical pharmacology 88 (12) (2022)
Lu Chen, Koen P van Rhee, Roeland E Wasmann, Elke H J Krekels, Marinus J Wiezer, Eric P A van Dongen, Paul E Verweij, Paul D van der Linden, Roger J M Brüggemann, Catherijne A J Knibbe
Total bodyweight and sex both drive pharmacokinetic variability of fluconazole in obese adults. The Journal of antimicrobial chemotherapy 77 (8) (2022)
Rob Christiaan van Wijk, Wanbin Hu, Sharka M Dijkema, Dirk-Jan van den Berg, Jeremy Liu, Rida Bahi, Fons J Verbeek, Ulrika S H Simonsson, Herman P Spaink, Piet H van der Graaf, Elke H J Krekels
Anti-tuberculosis effect of isoniazid scales accurately from zebrafish to humans. British journal of pharmacology 177 (24) (2020)
Lu Chen, Elke H J Krekels, Paul E Verweij, Jochem B Buil, Catherijne A J Knibbe, Roger J M Brüggemann
Pharmacokinetics and Pharmacodynamics of Posaconazole. Drugs 80 (7) (2020)
Bianca D van Groen, Wouter H Vaes, B Kevin Park, Elke H J Krekels, Esther van Duijn, Lenne-Triin Kõrgvee, Wioleta Maruszak, Grzegorz Grynkiewicz, R Colin Garner, Catherijne A J Knibbe, Dick Tibboel, Saskia N de Wildt, Mark A Turner
Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children. British journal of clinical pharmacology 85 (10) (2019)
Elke H J Krekels, Elisa A M Calvier, Piet H van der Graaf, Catherijne A J Knibbe
Children Are Not Small Adults, but Can We Treat Them As Such? CPT: pharmacometrics & systems pharmacology 8 (1) (2019)
Rob Christiaan van Wijk, Elke H J Krekels, Vasudev Kantae, Anita Ordas, Thijs Kreling, Amy C Harms, Thomas Hankemeier, Herman P Spaink, Piet H van der Graaf
Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol. The Journal of pharmacology and experimental therapeutics 371 (1) (2019)
Rob Christiaan van Wijk, Elke H J Krekels, Vasudev Kantae, Amy C Harms, Thomas Hankemeier, Piet H van der Graaf, Herman P Spaink
Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae. Scientific reports 9 (1) (2019)
Pascal Schulthess, Rob Christiaan van Wijk, Elke H J Krekels, James W T Yates, Herman P Spaink, Piet H van der Graaf
Outside-In Systems Pharmacology Combines Innovative Computational Methods With High-Throughput Whole Vertebrate Studies. CPT: pharmacometrics & systems pharmacology 7 (5) (2018)
Janneke M Brussee, Huixin Yu, Elke H J Krekels, Berend de Roos, Margreke J E Brill, Johannes N van den Anker, Amin Rostami-Hodjegan, Saskia N de Wildt, Catherijne A J Knibbe
First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates. CPT: pharmacometrics & systems pharmacology 7 (6) (2018)

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Publication Activity (10 Years)

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Elke H J Krekels