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CDSeqR: fast complete deconvolution for gene expression data from bulk tissues.

Kai KangCaizhi HuangYuanyuan LiDavid M UmbachLeping Li
Published in: BMC bioinformatics (2021)
The existing bulk RNA-seq repositories, such as TCGA and GTEx, provide enormous resources for better understanding changes in transcriptomics and human diseases. They are also potentially useful for studying cell-cell interactions in the tissue microenvironment. Bulk level analyses neglect tissue heterogeneity, however, and hinder investigation of a cell-type-specific expression. The CDSeqR package may aid in silico dissection of bulk expression data, enabling researchers to recover cell-type-specific information.
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