Natural history of Von Hippel-Lindau disease-associated and sporadic clear cell renal cell carcinoma: a comparative study.

Jie WangLei ZhangJianhui QiuZiao LiYucai WuCuijian ZhangLin YaoKan GongXue-Song LiLiqun Zhou

Published in: Journal of cancer research and clinical oncology (2021)

Sporadic ccRCC grew faster than VHL-associated RCC. High histologic grade, low VHL expression and negative PBRM1 expression were predictors of faster growth in sporadic ccRCC. A large initial MTD was a predictor of faster growth for VHL-associated RCC.

Keyphrases

late onset
poor prognosis
amyotrophic lateral sclerosis
renal cell carcinoma
binding protein
long non coding rna
early onset