Antibiotic prophylaxis in veterinary cancer chemotherapy: A review and recommendations.
Jocelyn L BissonD J ArgyleS A ArgylePublished in: Veterinary and comparative oncology (2018)
Bacterial infection following cancer chemotherapy-induced neutropenia is a serious cause of morbidity and mortality in human and veterinary patients. Antimicrobial prophylaxis is controversial in the human oncology field, as any decreased incidence in bacterial infections is countered by patient adverse effects and increased antimicrobial resistance. Comprehensive guidelines exist to aid human oncologists in prescribing antimicrobial prophylaxis but similar recommendations are not available in veterinary literature. As the veterinarian's role in antimicrobial stewardship is increasingly emphasized, it is vital that veterinary oncologists implement appropriate antimicrobial use. By considering the available human and veterinary literature we present an overview of current clinical practices and are able to suggest recommendations for prophylactic antimicrobial use in veterinary cancer chemotherapy patients.
Keyphrases
- endothelial cells
- end stage renal disease
- staphylococcus aureus
- papillary thyroid
- chemotherapy induced
- antimicrobial resistance
- induced pluripotent stem cells
- ejection fraction
- newly diagnosed
- primary care
- clinical practice
- chronic kidney disease
- pluripotent stem cells
- healthcare
- prognostic factors
- squamous cell
- emergency department
- rectal cancer
- lymph node metastasis