Preanalytical DNA assessment for downstream applications: How to optimize the management of human biospecimens to support molecular diagnosis-An experimental study.
Marina MordentiValentina CapicchioniSerena CorsiniManuela LocatelliElisabetta AbelliFederico BanchelliManila BoariniLuca SangiorgiPublished in: Journal of clinical laboratory analysis (2022)
Our findings confirm the reliability of peripheral blood samples in almost all the experimental conditions. Saliva and buccal swabs are efficient almost as well, while peripheral blood mononuclear cells, albeit remain a primary source of DNA for molecular screenings, represent a less efficient source.