Active cycle of breathing technique versus oscillating PEP therapy versus walking with huffing during an acute exacerbation of bronchiectasis: a randomised, controlled trial protocol.
Jennifer PhillipsWayne HingRodney PopeAshleigh CanovNicole HarleyAnnemarie L LeePublished in: BMC pulmonary medicine (2023)
Despite recommendations regarding the importance of ACT for individuals with bronchiectasis during an acute exacerbation, there is a gap in the literature regarding effectiveness of ACT when undertaken by individuals in this clinical state. This study will add to the evidence base regarding the effectiveness of commonly implemented ACTs during a hospital admission with an exacerbation of bronchiectasis. Additionally, it will contribute to knowledge of the long term effects on important and patient-centred outcomes, including incidence of future exacerbations, and HRQOL, which has not been previously established. Trial registration Registered on the Australian and New Zealand Clinical Trials Registry (ACTRN12621000428864).
Keyphrases
- chronic obstructive pulmonary disease
- cystic fibrosis
- respiratory failure
- clinical trial
- randomized controlled trial
- liver failure
- systematic review
- healthcare
- study protocol
- drug induced
- phase ii
- extracorporeal membrane oxygenation
- aortic dissection
- emergency department
- phase iii
- mechanical ventilation
- risk factors
- case report
- hepatitis b virus
- stem cells
- type diabetes
- open label
- bone marrow
- mesenchymal stem cells
- lower limb
- cell therapy