DNA mismatch repair system regulates the expression of PD-L1 through DNMTs in cervical cancer.

Fan GuoRuijiao LuWeina KongMiyessar AnwarYangchun Feng

Published in: Cancer cell international (2024)

PD-L1 is universal expressed on the surface of CC cells, dMMR status enhances the expression of PD-L1 on the surface of CC cells, dMMR states of CC are related to the demethylation status of the PD-L1 gene promoter region.

Keyphrases

induced apoptosis
poor prognosis
cell cycle arrest
dna methylation
gene expression
endoplasmic reticulum stress
oxidative stress
signaling pathway
binding protein
cell death
cell proliferation
pi k akt
nucleic acid