Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris.

Shengjun WangYongheng RongYaoguang WangDecai KongPeng George WangMin ChenYun Kong

Published in: Microbial cell factories (2020)

This strategy develops a simple glycoengineered yeast expression system to produce N-GlcNAc modified proteins, which could be further extended to different N-glycan structures. This system would provide a prospective platform for mass production of increasing novel glycoprotein drugs.

Keyphrases

poor prognosis
binding protein
recombinant human
high throughput
high resolution
protein protein
saccharomyces cerevisiae
drug induced
cell surface