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A Monoclonal Antibody to PACAP for Migraine Prevention.

Messoud AshinaRavinder PhulMelanie KhodaieElin LöfIoana Florea
Published in: The New England journal of medicine (2024)
In a phase 2 trial, a single intravenous infusion of 750 mg of Lu AG09222 showed superiority over placebo in reducing migraine frequency over the subsequent 4 weeks. (Funded by H. Lundbeck; HOPE ClinicalTrials.gov number, NCT05133323.).
Keyphrases
  • monoclonal antibody
  • low dose
  • high dose
  • quantum dots
  • gestational age
  • highly efficient
  • randomized controlled trial
  • clinical trial
  • phase iii